While I seem to have the right build strategy, diplomacy and a killer research strategy I have run into a roadblock in the late game stages. I get to the point of having the most powerful military and robust economy and I am limited in being to reach some enemies to take them out of the game because I can't reach them although I try to really research the most advanced life support technology. The result is that they get a chance to catch back up and there no is resolution to the game. I have won games with the best research and the most influence but I have won only once in conquer mode (and that was with a very configuration of empires).
Perhaps is just not impossible to achieve a conquer strategy when the other empires are not reachable. It may be that my ship designs are hindering me. Whatever it is I have not found a solution. Any help or suggestions would be great.