First off, this is a random bug that is cleared by reloading, so sending in a save file and a ticket on it might not be very helpful. But, if directed, I can send one in anyway when it happens.
Ever since the graphics were tweaked a while back, I can get a very bright orangey swirl in the background with a very washed out foreground. This is very hard on the eyes, and, subjectively, pretty ugly. A reload or two will usually clear it, though sometimes I have to quit the program altogether to clear it.
Here is a screenshot of what I am talking about:
All my drivers are up to date as well, before anyone asks. 